Introduction
A man contracts a deadly virus after handling fruit bats. A child falls ill from drinking unpasteurized milk. A farmer develops a fever after tending to sick livestock. These aren’t fiction—they’re real-world examples of zoonotic disease threats unfolding across the globe.
Zoonotic diseases, or zoonoses, are infections that spread between animals and humans. According to the CDC, over 60% of known human infectious diseases and around 75% of emerging ones have animal origins [1]. These threats are rising as climate change, urbanization, and global trade increase contact between people and animals [3].
How can we stay ahead of these threats before they trigger the next global health emergency?
What Are Zoonotic Disease Threats?
Zoonotic diseases are caused by bacteria, viruses, parasites, or fungi, and they can spread through direct contact, contaminated food or water, insect bites, or environmental exposure [1]. Some are mild; others can cause severe outbreaks.
Here are 15 significant zoonotic diseases everyone should know:
- Anthrax – Contracted from infected livestock or animal products, it can cause skin lesions, respiratory failure, or death [3].
- Brucellosis – Spread via unpasteurized dairy or animal contact, leading to fever, fatigue, and joint pain [2].
- Plague – Transmitted through fleas from rodents, it can be fatal without prompt treatment, though it’s now rare [2].
- Leptospirosis – Caused by bacteria in water contaminated with animal urine; can damage kidneys and liver [3].
- Q Fever – A respiratory disease in people who inhale particles contaminated with livestock waste [2].
- Salmonellosis – Commonly foodborne; linked to undercooked meat, eggs, and animal contact [1].
- Campylobacteriosis – Causes gastrointestinal illness from raw poultry or unclean water [2].
- Listeriosis – Found in deli meats, soft cheeses, and unpasteurized milk; can cause miscarriage or death in high-risk groups [1].
- Rabies – One of the deadliest diseases; spreads through bites from infected animals. 100% preventable by vaccination [4].
- Avian Influenza – Bird flu strains can jump to humans and cause respiratory failure [3].
- Swine Influenza – Flu viruses from pigs can infect humans, such as the H1N1 pandemic in 2009 [2].
- Viral Hemorrhagic Fevers (e.g., Ebola, Marburg) – Spread through body fluids from infected animals or humans; have high fatality rates [3].
- Toxoplasmosis – A parasitic infection from cat feces or raw meat, especially dangerous during pregnancy [1].
- Echinococcosis – Caused by tapeworms in dogs or livestock; leads to cysts in human organs [4].
- Cysticercosis – A parasitic disease from ingesting pork tapeworm eggs; can cause seizures and brain damage [2].
Why Zoonotic Disease Threats Are Growing
Multiple forces are making zoonotic diseases more common and harder to control:
- Urban expansion into wildlife habitats increases contact between people and animals [3].
- Climate change shifts the range of vectors like mosquitoes and ticks [5].
- Intensive farming and poor sanitation provide ideal conditions for pathogens to spread [4].
- International travel and trade allow diseases to move rapidly across continents [1].
These interconnected drivers mean even a local outbreak can quickly become a global emergency.
One Health: The Smartest Strategy Against Zoonotic Threats
Zoonotic disease prevention requires collaboration across human, animal, and environmental health—the core of the One Health approach.
Key One Health interventions include:
- Animal vaccination (e.g., rabies, brucellosis prevention in livestock) [4].
- Safe food handling and improved slaughterhouse hygiene.
- Rodent and vector control to prevent disease spread.
- Surveillance and early warning systems in farms and communities [3].
- Sanitation and clean water access in rural areas.
- Public education to reduce risky human-animal interactions.
- Land use planning that protects wildlife habitats and prevents deforestation.
When sectors work together, outbreaks can be prevented or contained before they spiral into epidemics.
Conclusion
Zoonotic disease threats are not just health concerns—they’re environmental and economic risks. From rabies to Ebola, these diseases illustrate how deeply connected our health is to that of animals and the environment.
We all have a role to play. Whether you’re a policymaker, veterinarian, health worker, or pet owner, your actions—from reporting sick animals to supporting One Health policies—can help reduce the risk.
When animals suffer, people follow. But when we protect all health, everyone thrives.
References
- Centers for Disease Control and Prevention (CDC). (2024). About Zoonotic Diseases. Available at: https://www.cdc.gov/one-health/about/about-zoonotic-diseases.html
- Centers for Disease Control and Prevention (CDC). (2017). Prioritizing Zoonotic Diseases for Multisectoral, One Health Coordination in the United States. Available at: https://www.cdc.gov/one-health/media/pdfs/us-ohzdp-report-508.pdf
- World Health Organization (WHO). (2019). Taking a Multisectoral, One Health Approach: A Tripartite Guide to Addressing Zoonotic Diseases in Countries. Available at: https://www.who.int/publications/i/item/9789241514934
- Food and Agriculture Organization of the United Nations (FAO). (2025). Zoonoses – One Health. Available at: https://www.fao.org/one-health/areas-of-work/zoonoses/en
- Jones, K. E., Patel, N. G., Levy, M. A., Storeygard, A., Balk, D., Gittleman, J. L., & Daszak, P. (2008). Global trends in emerging infectious diseases. Nature, 451(7181), 990–993. https://doi.org/10.1038/nature06536