The ECDC Communicable Disease Threats Report (CDTR) is a weekly bulletin for epidemiologists and health professionals on active public health threats. This issue of the CDTR covers the period 19-25 October 2024 and includes updates on avian influenza A(H5N1), Marburg virus disease, Mpox, dengue, West Nile virus infections, cholera and an overview of respiratory virus epidemiology in the EU/EEA.